CAGR: 6.10%Current Market Size: USD 3.6 BillionFastest Growing Region: APAC
Largest Market: North AmericaProjection Time: 2023-2030Base Year: 2022
The global bone graft and substitutes market is expected to grow from USD 3.6 billion in 2022 to USD 5.78 billion by 2030, at a CAGR of 6.10% during the Projection period 2023-2030. The growth of the bone graft and substitutes market is mainly driven owing to the rising demand for dental bone grafts.
A surgical procedure called "bone grafting" involves replacing lost bone. In bone grafting treatments, various types of bone grafts including synthetic, allograft, and autologous bone transplants are employed. The process of interdigitating and enveloping the donor bone tissue with the new bone formed by the recipient is known as the incorporation of bone transplant. It is adaptable and repairs lost bone tissue while promoting bone growth through natural processes. The best sort of bone grafts for replacing missing bones are natural bone grafts, which have the highest success rates. Growth in the global bone substitutes and grafts market is anticipated to be fueled by the rising incidence of bone cancer. Over the course of the Projection period, the global bone grafts and substitutes market is anticipated to rise as a result of the rising incidence of bone cancer. For instance, the American Society of Clinical Oncology (ASCO) estimates that 3,450 Americans of all ages received a primary bone cancer diagnosis in 2017. The U.S. market for bone cancer treatments is thus anticipated to rise as a result of new cases of bone cancer. Additionally, the market is expanding because of the increasing use of dental bone grafts. Dental bone grafts' better success rate is increasing demand for them. According to Minim Invasive Surg in 2018, a variety of different bone problems were treated using minimally invasive techniques. Additionally, it mentioned that the United States performed 400,000 spinal fusion procedures yearly. Such elements influence market expansion favorably. Additionally, the bone grafts and substitutes market is benefiting from the growing trend of minimally invasive operations (MIS).
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Market Dynamics:
Drivers:
One of the key factors accelerating the growth and demand of the bone grafts and substitutes market is the sharp rise in cases of musculoskeletal problems and the rapid expansion of biocompatible synthetic bone grafts. Additionally, the aging population and the quickening pace of technical progress in the medical area are both fueling the expansion of the global bone graft and substitute market during the Projection period.
Restraints:
Lack of bone development or partial bone formation, unfavorable tissue reactions, and infections of the bone and soft tissue are a few of the substitutes' growing clinical problems. As a result, it is anticipated that this factor will restrain market growth over the Projection period. These restrictions and the rising hazards associated with using these products have prompted the U.S. FDA and the producers to recall the goods. It is anticipated that these recalls will discourage consumers from using alternatives, hurting the companies' ability to build their brands. For instance, Aziyo Biologics recalled a significant amount of FiberCel, an allograft product, according to an article in Becker's Healthcare from June 2021. After numerous recipients of the allograft tested positive for TB, the allograft was recalled.
Opportunities:
The market's expansion is also being aided by the increasing use of health insurance and specialty orthopedic clinics. Another important element driving the growth of the bone grafts and substitutes market is the increased consumer awareness of appearance and preference for natural or organic items. A strong rate of industrial expansion throughout the Projection period will also be ensured by rising disposable income in emerging economies.
Challenges:
The bone grafts and substitutes market will be constrained in its growth by the high cost of surgeries and numerous ethical concerns associated with bone grafting procedures, whilst the industry's expansion could be threatened by certain clinical restrictions and high morbidity.
Segmentation Analysis:
The global bone graft and substitutes market has been segmented based on type, application, end-user, and region.
By Type
The type segment is an allograft, synthetic, Demineralized Bone Matrix (DMI), and xenograft. The allograft segment led the largest share of the bone graft and substitute market with a market share of around 40% in 2022. Allograft use is expanding as a result of their advantages, including osteo conductivity and rapid structural support. They also don't need a second surgery, which speeds up wound healing and cuts down on surgical time. These are frequently applied to the knee, hip, and spine. Demineralized bone matrices, which come in a variety of sizes and shapes such as chips, pellets, and granules, are readily accessible. Additionally, they exhibit both osteoinductive and osteoconductive capabilities, which boosts their appeal and the market's growth.
By Application
The application segment is dental, foot and ankle, long bone, craniomaxillofacial, joint reconstruction, and spinal fusion. The spinal fusion segment led the largest share of the bone graft and substitutes market with a market share of around 29% in 2022. The increase in spondylosyndesis procedures using bone graft materials can be blamed for the growth of this segment. Additionally, the growing elderly population who are more susceptible to orthopedic conditions is driving up demand for corrective surgery, which is expected to accelerate market growth in the Projection period. The World Health Organization predicts that the elderly population will double, from 12% to 22%, between 2015 and 2050. Through the Projection period, it is predicted that the segment will benefit greatly from rising graft utilization for dental treatments. The grafts are typically utilized as a scaffold and filler to aid in the development of new bone and accelerate recovery.
By End-User
The end-user segment is hospitals, specialty clinics, and others. The hospital’s segment led the largest share of the bone graft and substitutes market with a market share of around 36% in 2022. The numerous orthopedists employed by hospitals are blamed for the segmental increase. Additionally, the hospital market is anticipated to be driven by an increase in patient visits to choose from a variety of spinal and joint reconstructive operations throughout the Projection period. For instance, a Healthline Media article from April 2020 states that in the U.S., total knee replacement surgery is now commonly performed at many facilities, with an estimated 600,000 procedures done each year.
Global Bone Graft and Substitutes Market- Sales Analysis.
The sale of bone graft and substitutes market expanded at a CAGR of 4.80% from 2016 to 2022.
Bone grafts are employed for a variety of reasons, including the filling of holes caused by cysts, tumors, or other conditions, the stimulation of the healing of fractures that have not responded to initial therapy, and others. The use of bone transplants in orthopedic operations is common. These procedures are categorized as elective surgeries, and during the Covid-19 outbreak, the majority of elective surgeries were delayed or canceled. As a result, the need for orthopedic surgery equipment, such as bone grafts and substitutes, dramatically decreased. The production of the gadgets was further slowed down by protracted factory closures by market participants in a number of different countries.
The minimally invasive techniques provide a number of benefits, including little discomfort, and less tissue damage. MIS is thus preferred by medical practitioners over open surgery. Additionally, over the course of the Projection period, market players should benefit from technological advancements in the incorporation of human growth factors into bone grafts that have osteoconductive and osteoinductive properties, such as demineralized bone matrix, bone morphogenetic proteins, and platelet-rich plasma (PRP).
Thus, owing to the aforementioned factors, the global bone graft and substitutes market is expected to grow at a CAGR of 6.10% during the Projection period from 2023 to 2030.
By Regional Analysis:
The regions analyzed for the bone graft and substitutes market include North America, Europe, South America, Asia Pacific, the Middle East, and Africa. North America region dominated the bone graft and substitutes market and held a 40% share of the market revenue in 2022.
Global Bone Graft and Substitutes Market- Country Analysis:
Germany's bone graft and substitutes market size was valued at USD 0.0051 billion in 2022 and is expected to reach USD 0.0074 billion by 2030, at a CAGR of 4.8% from 2023 to 2030. Regional growth is predicted to be boosted by the expanding number of strategic efforts, including product launches, approvals, acquisitions, mergers, partnerships, and joint ventures.
China’s bone graft and substitutes market size was valued at USD 0.0071 billion in 2022 and is expected to reach USD 0.0110 billion by 2030, at a CAGR of 5.7% from 2023 to 2030. The three main factors driving the region's growth are rising healthcare costs, increased awareness of commercially accessible technological products, and accessibility to a comprehensive healthcare system.
India's Bone graft and substitutes market size was valued at USD 0.0063 billion in 2022 and is expected to reach USD 0.0093 billion by 2030, at a CAGR of 5% from 2023 to 2030. To accommodate a bigger patient pool, developing nations like India concentrate on building medical facilities such as specialty clinics. In the long run, it is anticipated that the market expansion will be supported by the intense focus on enhancing healthcare infrastructure.
Key Industry Players Analysis:
To increase their market position in the global bone graft and substitutes business, top companies focus on tactics such as adopting new technology, mergers & acquisitions, product developments, collaborations, partnerships, joint ventures, etc.
Latest Development:
Report Metrics
Report Attribute |
Details |
Study Period |
2022-2030 |
Base year |
2022 |
CAGR (%) |
6.10% |
Market Size |
3.6 billion in 2022 |
Projection period |
2023-2030 |
Projection unit |
Value (USD) |
Segments covered |
By Type, By Application, By End-User, and By Region. |
Report Scope |
Revenue Projection, competitive landscape, company ranking, growth factors, and trends |
Companies covered |
AlloSource, DePuySynthes, Inc., Baxter, Nuvasive, Inc., Smith & Nephew, Medtronic, Orthofix Holdings, Inc., GeistlichPharma AG, OST Development, TBF Tissue Engineering, Zimmer Biomet, Wright Medical Group N.V., Stryker Corporation, and Biobank. |
By Type |
|
By Application |
|
By End-User |
|
Regional scope |
|
Scope of the Report
Global Bone Graft and Substitutes Market By Type:
Global Bone Graft and Substitutes Market By Application:
Global Bone graft and substitutes market By End-User:
Global Bone Graft and Substitutes Market By Region:
Global bone graft and substitutes market is expected to reach USD 5.78 billion by 2030.
The bone graft and substitutes market is projected to have a CAGR of 6.10%.
One of the key factors accelerating the growth and demand of the bone grafts and substitutes market is the sharp rise in cases of musculoskeletal problems and the rapid expansion of biocompatible synthetic bone grafts.
Based on the type, the global bone graft and substitutes market has been segmented into allograft, synthetic, Demineralized Bone Matrix (DMI), and xenograft.
Leading market players active in the global bone graft and substitutes market are AlloSource, Baxter, Johnson & Johnson Services, Inc., Smith & Nephew, Stryker, Orthofix Medical Inc., Zimmer Biomet, Medtronic, Geistlich Pharma AG, Dentsply Sirona, Biobank, Wright Medical Group N.V., Globus Medical, BioHorizons, Integra LifeSciences, Arthrex, Inc., Artoss, Inc., ACE Surgical Supply Co., Inc., ACE Surgical Supply Co., Inc., Institut Straumann AG, and NuVasive, Inc., among other
Political Factors- The long-term viability and profitability of the bone graft and substitute market are significantly influenced by political issues. The bone graft and substitution market are more sensitive to changes in various nations' political contexts because of its prominence in the global arena. In a political setting, diversifying systematic risks is essential for success in a fast-paced, global corporate world. A nation's political climate is composed of numerous variables. During the process of strategic planning, the bone graft and substitute market needs to take into account the following political factors: A stable and welcoming business climate with predictable market growth tendencies is provided by high political stability. However, political instability scares away investors and undermines stakeholder confidence in the economy and, as a result, organisational effectiveness.
Economic Factors- The bone graft and substitution market must comprehend economic elements including inflation, saving rates, labour market circumstances, and foreign exchange/interest rates because they affect the nation's overall economic climate. The bone graft and substitution market can predict the industry and organization's growth trajectory by having a thorough awareness of the economic environment. The bone graft and substitution market must take into account the following economic aspects in order to make wise decisions: Organizational performance is directly impacted by a nation's economic development. Growing economies present a Bone graft and substitution market with numerous prospects for expansion. In a similar vein, it's critical to comprehend the stage of the industrial lifecycle. Due to market saturation, entering mature sectors might be more difficult than entering businesses in the growth stage.
Social Factors- For global commercial enterprises like Bone graft and substitution market changes in demographic patterns including population ageing, migration trends, and socioeconomic factors are of the utmost importance. The bone graft and substitution market might choose the appropriate market segment or sectors with strong growth potential by looking at the demographic factors. Migration has an impact on business and marketing strategy as well. The bone graft and substitution market must comprehend how society as a whole feels about migration because this feeling can affect a company's capacity to hire foreign management in the host nation. Any society's acceptance of hierarchy and income disparity can be seen in the power distance. When entering markets with high or low power distance, the Bone graft and substitution market must modify its business management procedures.
Technological Factors- The use of cutting-edge marketing strategies to improve customer collaboration has been facilitated by the growth of information and communication technologies. Social media usage has become widespread in today's business climate. The bone graft and substitution market can exploit the potential presented by social media marketing to boost business success. Technological developments can be exploited to launch creative social media marketing for creating online brand communities. To keep ahead of the competition, the Bone graft and substitution market need carefully analyse the ongoing technical developments. The potential for the 5G to improve business outcomes through improved user experience, better speed, and increased access should be closely monitored. Such technological advancements have the potential to significantly modify a sector and change the course of success.
Environmental Factors- Businesses have been forced to implement cutting-edge recycling and waste management strategies due to the combination of rising environmental degradation and technological innovation. Recycling is almost a corporate standard in several nations. Furthermore, the bone graft and substitution market recognises the importance of implementing effective waste management procedures in organisational divisions situated in or close to urban regions. Many nations have established stringent regulations to safeguard their metropolitan regions through efficient garbage management. Some nations provide financial aid to encourage the use of renewable energy sources. To ensure long-term sustainability, the Bone graft and substitution market can profit from it and make investments in renewable technology. Due to improved brand perception, this investment will also result in higher stakeholder satisfaction and a larger consumer base.
Legal Factors- As certain nations have severe requirements to protect labour safety, the bone graft and substitution market must abide by the employee/labour health and safety legislation. In a similar vein, anti-discrimination laws (such as equal employment opportunity laws) also need to be carefully considered when developing human resource practises as discriminatory lawsuits against employers harm the organisational image and affect organisations' capacity to attract and retain talent. The privacy and security concerns of consumers have made data protection a crucial issue. The bone graft and substitution market must research data protection laws in order to safeguard client information. Laws are also in place to limit prices, guarantee a particular level of quality, and shield consumers from dishonest marketing.
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