CAGR: 6.7%Current Market Size: USD 15 BillionFastest Growing Region: APAC
Largest Market: North AmericaProjection Time: 2023-2030Base Year: 2022
The global ocular drug delivery market is expected to grow from USD 15 billion in 2022 to USD 25.2 billion by 2030, at a CAGR of 6.7% during the Projection period 2023-2030. The growth of the ocular drug delivery market is mainly driven by the rise in ophthalmic disorders.
Treatment of ophthalmic illnesses involves ocular medication administration. Ophthalmic illnesses, which mostly fall into the categories of the anterior segment and posterior segment, affect different regions of the eye anatomy. Ocular medications are placed directly on or close to the afflicted area to ensure quick absorption and quick effect. For treating illnesses of the anterior eye segment, topical ocular medication formulations are typically offered in liquid form as solutions, suspensions, and emulsions. Modern therapies, like implants and injections, are used to address posterior segment illnesses. Polymers, bioadhesive gels, and hydrogels are among the substances employed in ocular medication delivery. By avoiding the natural barriers associated with the architecture of the eye, new drug delivery technologies improve therapeutic agent penetration and provide long-lasting effects. Conventional drug delivery can effectively treat anterior segment disorders, while new drug delivery methods such as intravitreal, subconjunctival, and suprachoroidal injections are used to treat posterior segment diseases. Longer-acting treatment systems and dosage formulations are currently being researched. The frequency of ocular diseases and disorders has considerably increased in recent years as a result of factors like an aging population (which causes macular degeneration and cataracts), excessive eye strain from long work hours, and rising diabetes rates, which cause retinopathy.
Sample Request: - Global Ocular Drug Delivery Market
Market Dynamics:
Drivers:
The demand is expected to increase as a result of rising research and development efforts to create and introduce novel ophthalmic medications, as well as a number of strategic initiatives anticipated by the major players. Additionally, the market for ophthalmic medications is projected to rise as a result of unmet needs in ophthalmology. Nearly 2.2 billion people are predicted to have distant or near vision impairment disorders, and of these, at least half, or 1 billion instances, can be avoided with the aid of adequate treatment, according to the World Health Organization's October 2021 report on blindness and vision impairment. High age is the main factor in blindness and vision impairment. The financial burden on the governments is increasing as a result of this high incidence.
Restraints:
Ocular inserts and implants offer benefits such as excellent corneal penetration, a larger region for medication to dissolve, and sustained pharmaceutical release. However, the hardness of the implants causes a foreign body sensation in the eye, which causes discomfort accompanied by irritability, medication dilution, and excessive lachrymation. Additionally, the term "nasolacrimal drainage through lacrimal canaliculi" alludes to the drug's systemic absorption through the nasal mucosa or gastrointestinal tract, which results in a reduction in the drug's overall volume. One of the problems limiting the effectiveness of ocular drug delivery is the decrease in drug volume and the infrequent occurrence of allergic reactions in the lacrimal system following drug passage.
Opportunities:
The market for ocular drug delivery systems is anticipated to see more growth if ocular penetration enhancers such as para-cellular pathways and phase transition systems are used. Additionally, the protective barrier mechanisms of the human eye impair the effectiveness of medication delivery, opening the door for the development of methods to get beyond these barriers while administering drugs. EyeGate Pharmaceuticals, Inc. released interim results from a Phase 1b/2a trial with the iontophoretic EGP-437 in June 2016. These results showed a favorable safety profile and effective bypass mechanisms.
Challenges:
A further factor that is projected to function as a barrier to improved drug delivery technologies in the worldwide ocular drug delivery technologies market is the decrease in patient compliance as well as adherence to novel ocular medicines due to high cost and related difficulties.
Segmentation Analysis:
The global ocular drug delivery market has been segmented based on technology, dosage form, product type, drug class, and region.
By Technology
The technology segment is nano-particle drug delivery systems, implantable ocular drug delivery systems, and particulate drug delivery systems. The nano-particle drug delivery systems segment led the largest share of the ocular drug delivery market with a market share of around 45% in 2022. In contrast to typical eye drops, nanoparticles have been developed to overcome obstacles, improve drug penetration at the target region, and prolong drug levels by a few internals of medication administrations in lower dosages.
By Dosage Form
The dosage form segment is suspension, gels, solution, emulsion, and ointments. The solution segment led the largest share of the ocular drug delivery market with a market share of around 40.3% in 2022. The expanding OTC availability of eye drops, patient compliance issues, and the prevalence of eye illnesses all influence the eye drop market's growth. In addition, it is predicted that new product introductions with altered formulations would meet market demand. For instance, Alcon announced the release of their cutting-edge Systane Complete preservative-free eye drop in January 2022. Additionally, it is projected that the availability of cutting-edge technologies to improve bioavailability and physiochemical stability will fuel segment demand. For instance, Bosch and Lomb announced the launch of their hydration lubricant eye drop Biotrue in the United States in July 2021. This product is free of preservatives and comes from a natural source.
By Product Type
The product type segment is OTC Drugs and prescription drugs. The prescription drugs segment led the largest share of the ocular drug delivery market with a market share of around 62.3% in 2022. The increase in conditions like AMD and diabetic retinopathy is responsible for the prescription medicine market's expansion. Improved safety and efficacy are two more variables that could increase demand in the prescription market. Lotemax gel/ointment, Zylet, Durezol, Bepreve (bepotastine besilate ophthalmic solution), and prescription artificial tears are a few of the medications offered in this market. Antihistamine Bepreve is used to treat allergic conjunctivitis. Some pharmaceutical medicines have lubricating and moisturising ingredients that temporarily increase tear production. Prescription drugs are chosen over over-the-counter ones because they are thought to be the most effective in treating ocular conditions.
By Drug Class
The drug class segment is anti-glaucoma, antiallergy, anti-VEGF agents, and anti-inflammatory. The anti-VEGF agents segment led the largest share of the ocular drug delivery market with a market share of around 40.3% in 2022. The expanding OTC availability of eye drops, patient compliance issues, and the prevalence of eye illnesses all influence the eye drop market's growth. In addition, it is predicted that Rising anti-VEGF agent usage and demand, as well as the presence of major market players with extensive product lines, all contribute to the segment's growth. For instance, Genentech USA's LUCENTIS is a prescription drug for the management of individuals with myopic choroidal neovascularization, AMD, and diabetic retinopathy. Furthermore, Avastin, LUCENTIS, and other market leaders performed well, which is another factor contributing to the segment's growth. The attention of stakeholders on the development of treatments with prolonged action is expanding because the current class of anti-VEGF drugs is effective but short-lived. Opthea, Lupin Limited, and Kodiak Sciences Inc. are a few businesses with exciting pipeline products.
Global Ocular Drug Delivery Market - Sales Analysis.
The sale of the ocular drug delivery market expanded at a CAGR of 4% from 2016 to 2022.
For the treatment of macular degeneration, glaucoma, presbyopia, allergies, anti-viral, dry eye, anti-infective, and anti-inflammatory indications, ocular drug delivery systems are platforms developed for dispensing pharmaceutical, biologic, biopharmaceutical, and botanical medicines. For the aforementioned ocular diseases, various conventional and novel drug delivery systems, including ointments, emulsions, suspensions, aqueous gels, nano micelles, liposomes, dendrimers, implants, contact lenses, nanoparticles, Nano suspensions, microneedles, and in situ thermosensitive gels, have been developed to overcome ocular drug delivery barriers and improve bioavailability. The development of methods to enhance the effectiveness of spatiotemporal drug administration is the main focus of research on significant market participants. For instance, pSivida Corp. revealed in May 2017 that phase 3 trials for its Durasert, a three-year uveitis implant, had produced positive 12-month follow-up data that had improved the management of posterior unectitis infection.
The efficacy of cutting-edge ocular medication delivery technologies is anticipated to rise as more research is done on novel drug delivery treatments for posterior eye therapy using implantable devices and micro- and nanoparticles. Companies that specialize in ocular drug delivery technology are continually spending more on research and development. Throughout the projection period, this tendency is probably going to persist. For instance, in order to create platforms for ocular medication delivery technologies, Valeant Pharmaceuticals International, Inc. spent US$ 421.0 Mn on research & development in 2016. A significant financial investment is necessary while innovative ocular medication delivery systems are being developed. The overall cost of research and development, as well as partnerships and licensing agreements with other research institutes, are expected to increase dramatically with the increase in new entrants.
Thus, owing to the aforementioned factors, the global ocular drug delivery market is expected to grow at a CAGR of 6.7% during the Projection period from 2023 to 2030.
By Regional Analysis:
The regions analyzed for the ocular drug delivery market include North America, Europe, South America, Asia Pacific, the Middle East, and Africa. The North America region dominated the ocular drug delivery market and held a 38.2% share of the market revenue in 2022.
Global Ocular Drug Delivery Market - Country Analysis:
Germany's ocular drug delivery market size was valued at USD 1.14 billion in 2022 and is expected to reach USD 1.9 billion by 2030, at a CAGR of 6.8% from 2023 to 2030.
Germany has rather tight regulatory standards. Consequently, getting drug approvals is a challenging task. The second largest market in Europe is Germany. Some of the top players want to increase their presence in Germany. For instance, AddLife AB, a life science independent operator, has acquired Vision Ophthalmology Group GmbH. AddLife AB serves both the public and private sectors in Europe with high-quality goods and services in a range of therapeutic fields.
China’s ocular drug delivery market size was valued at USD 1.17 billion in 2022 and is expected to reach USD 2.01 billion by 2030, at a CAGR of 7% from 2023 to 2030.
The market being examined in the region is also anticipated to grow as a result of the rising number of product and medicine launches and the firms' increased focus on research and development operations. For instance, Arctic Vision's Investigational New Drug (IND) application for a Phase III study of ARVN003 (pilocarpine microdose ophthalmic solution) to treat presbyopia was authorised by the China National Medical Products Administration's Center for Drug Evaluation in September 2021. (CDE, NMPA).
India's ocular drug delivery market size was valued at USD 0.9 billion in 2022 and is expected to reach USD 1.5 billion by 2030, at a CAGR of 6.9% from 2023 to 2030.
Due to an increase in the elderly population, an increase in diabetic patients as a result of changing eating patterns and genetic influences, and an increase in the number of awareness campaigns for eye care and treatment
Key Industry Players Analysis:
To increase their market position in the global ocular drug delivery market business, top companies focus on tactics such as adopting new technology, mergers & acquisitions, product developments, collaborations, partnerships, joint ventures, etc.
Latest Development:
Report Metrics
Report Attribute |
Details |
Study Period |
2022-2030 |
Base year |
2022 |
CAGR (%) |
6.7% |
Market Size |
15 billion in 2022 |
Projection period |
2023-2030 |
Projection unit |
Value (USD) |
Segments covered |
By Technology, By Dosage Form, By Product Type, By Drug Class and By Region. |
Report Scope |
Revenue Projection, competitive landscape, company ranking, growth factors, and trends |
Companies covered |
Graybug Vision Inc., URSAPHARM Arzneimittel GmbH, Allergan Plc., Alimera Sciences, Ocular Therapeutix, Inc., Taiwan Liposome Company Ltd., pSivida, Santen Pharmaceutical Co., Ltd, Eyegate Pharma, Envisia Therapeutics, Vision Ophthalmology Group GmbH, Valeant Pharmaceuticals International, Inc, and Clearside Biomedical. |
By Technology |
|
By Dosage Form |
|
By Product Type |
|
By Drug Class |
|
Regional scope |
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Scope of the Report
Global Ocular Drug Delivery Market By Technology:
Global Ocular Drug Delivery Market By Dosage Form:
Global Ocular Drug Delivery Market By Product Type:
Global Ocular Drug Delivery Market By Drug Class:
Global Ocular Drug Delivery Market By Region:
Global ocular drug delivery market is expected to reach USD 25.2 billion by 2030.
The ocular drug delivery market is projected to have a CAGR of 6.7%.
The demand is expected to increase as a result of rising research and development efforts to create and introduce novel ophthalmic medications, as well as a number of strategic initiatives anticipated by the major players. Additionally, the market for ophthalmic medications is projected to rise as a result of unmet needs in ophthalmology.
Based on the dosage form, the global ocular drug delivery market has been segmented into suspension, gels, solution, emulsion, and ointments.
Leading market players active in the global ocular drug delivery market are Graybug Vision Inc., URSAPHARM Arzneimittel GmbH, Allergan Plc., Alimera Sciences, Ocular Therapeutix, Inc., Taiwan Liposome Company Ltd., pSivida,, Santen Pharmaceutical Co., Ltd, Eyegate Pharma, Envisia Therapeutics, Vision Ophthalmology Group GmbH, Valeant Pharmaceuticals International, Inc, Clearside Biomedical among others.
Political Factors- The ocular drug delivery market should carefully study the criticisms made by pressure groups, social and environmental activists, and labour unions because they are essential to the creation of legislation. Close collaboration with these groups may enhance the ocular drug delivery market's ability to engage the community and achieve long-term corporate goals. A robust governance framework and a democratic political environment also improve the business environment for multinational firms, such as the ocular drug delivery market. The environment becomes increasingly hazy as a result of frequent changes in government policy, which is bad for business growth. Because a change in leadership may impact the government's priorities for the development of specific industries, the ocular drug delivery market must stay abreast of political changes in the country.
Economic Factors- Because operating in highly efficient financial markets increases a company's liquidity position and strengthens its potential to enter new markets, the efficiency of the financial market has an impact on the ocular drug delivery market and the market's plan for worldwide expansion. The health and efficiency of the financial markets will determine the ocular drug delivery market's capacity to raise capital at competitive rates. ocular drug delivery market is impacted by the current economic structure, which also supports the market's commercial activities. A structure with the perfect or monopolistic competition will not have the same economic or regulatory environment as one with an oligopolistic or monopolistic structure.
Social Factors- The power distance indicates a society's acceptance of hierarchy and income inequality. The ocular drug delivery market must adapt its business management practices when entering markets with high or low power distance. The growing inequality in many countries is altering the power structure, which has important implications for multinational firms like the ocular drug delivery market. For the ocular drug delivery market to modify its marketing and communication tactics, it needs to conduct research on the generally accepted gender norms. Societies with fewer gender stereotypes will employ different marketing and human resource strategies than traditional, patriarchal civilizations with well-defined gender roles.
Technological Factors- The ocular drug delivery market must consider both the micro and macro expenditures made by rivals in order to comprehend how new technologies affect the firm's value chain and present cost structure. Research and development efforts are essential in a situation where creative disruption is common. The ocular drug delivery market should invest in disruptive technologies and then reinvest the profits in the creation of new disruptive technologies in order to optimize revenues in this scenario. The use of new technology has cut the time needed to produce new items.
Environmental Factors- More people are choosing to use green or eco-friendly products. The market for ocular drug delivery market can take advantage of the opportunity and apply green business practices to win over stakeholders. Due to regulatory organizations' emphasis on assuring compatibility with environmental requirements, priorities for product innovation are changing. The ocular drug delivery market must prioritize promoting the environmental friendliness of its goods over conventional value propositions. If the ocular drug delivery market constantly depletes resources, it may come under fire from the media, environmental groups, consumers, and the general public. The ocular drug delivery market must examine the nation's unique environmental regulations to find out which resources (such as water, electricity, etc.) are scarce or which species are threatened, and whose overuse can pose problems for the company.
Legal Factors- Data protection has become a critical problem due to consumers' worries about their privacy and security. The ocular drug delivery market must investigate data protection rules in order to protect consumer data. Laws are also in place to control costs, ensure a certain standard of quality, and protect consumers from misleading advertising claims. The ocular drug delivery market must take into account a few factors in order to comply with consumer protection laws. Intellectual property laws are designed to protect the valuable ideas and patents that businesses possess. ocular drug delivery market position compared to other market participants may be undermined by losing competitive advantage as a result of a failure to uphold intellectual property rights.
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