CAGR: 9.3% Current Market Size: USD 201.40 Billion Fastest Growing Region: APAC
Largest Market: North AmericaProjection Time: 2022-2029Base Year: 2021
The global Topical drug delivery market is expected to grow from USD 201.40 billion in 2021 to USD 403.08 billion by 2029, at a CAGR of 9.3% during the projection period 2022-2029. The increasing prevalence of diabetes, rising occurrence of burn injuries, and an upsurge in the prevalence of dermal diseases have driven the growth of the global market.
The topical drug delivery (TDD) system involves a way to deliver medication and bring the drug substance into contact with the skin. These drugs are mainly applied to a certain part of the body. Usually, the skin treats different ailments. After the application on the skin, the drug primarily enters through the stratum corneum and passes via the deeper epidermis and dermis with no drug accumulation in the dermal layer. In addition, the process of TDD administers drugs into the body via different routes, including skin, nasal, vaginal, rectal, and ophthalmic.
The most common forms of topical drugs comprise lotions, patches, gels, and powders; however, they are mainly formulated as ointments or creams. It offers benefits such as fewer risks of gastrointestinal difficulties, ease of administration, enhanced suitability for self-medication, and elimination of limitations associated with oral delivery, such as vomiting and low bioavailability.
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Market Dynamics:
Drivers:
There is a significant prevalence of skin diseases in the general population across different regions of the globe. The world has been observing an upsurge population of common skin conditions such as acne, benign tumors, contact dermatitis, psoriasis, cancers, and atopic dermatitis (also called eczema). For instance, according to the American Academy of Dermatology, 84.5 million (one in four) people in the U.S. were impacted by skin diseases that accounted for about $75 billion in costs to the U.S. health care system in the form of preventative, medical, and prescription & non-prescription drug costs.
However, topical drugs have been a mainstay in treating skin disorders around the globe due to their easy application and lower risk of systemic side effects. Hence, the increased skin disease prevalence has driven the global market's growth.
Burn injuries are one of the most devastating of all injuries and account for the fourth most common kind of trauma globally, following traffic accidents, falls, and interpersonal violence. For instance, according to the WHO, an assessed 180,000 deaths are caused by burns every year, out of which the vast majority occur in developing and underdeveloped countries. Further, according to the Lancet Public Health, one of the leading journals in global health, burns wounds were one of the main reasons for disability, with over 8 million disability-adjusted life-years (DALYs).
Burn wounds are mainly treated with the help of topical agents as well as wound dressings according to their extent and stage. Therefore, the rising occurrence of burn injuries creates demand for topical drug delivery.
Restraints:
An allergy to topical drug delivery can lead to a range of reactions, including contact urticarial, anaphylaxis, irritant contact dermatitis, and photosensitivity. Also, there are some severe allergic reactions due to topical drugs. In addition, salicylate and benzocaine are among the active ingredients in several topical drug formulations, which leads to allergies. However, the allergies triggered by such drugs can be diagnosed with the help of a patch test which detects contact allergens. This factor may hamper the growth of the global market to some extent during the projection period.
Opportunities:
Within the home care settings, the trend of self-administration of drugs has been a prominent factor contributing to the demand for topical drug delivery systems. Closure of regular OPDs due to the COVID-19 pandemic and the increased geriatric population, has further pushed demand for self-administration of topical drugs across the home care settings.
Furthermore, topical drugs provide painless and suitable self-administration for patients. Hence, self-medication with over-the-counter medicines such as topical drugs has become an increasingly popular practice across the globe. This factor has created lucrative growth opportunities for the global market.
Challenges
Market withdrawals, recalls, and safety alerts published by government agencies such as the U.S. Food and Drug Administration poses significant challenges to the global market. For instance, in May 2022, Teva Pharmaceuticals USA Inc. recalled 353,964 tubes of prilocaine 2.5% and lidocaine 2.5% cream owing to deviations from Current Good Manufacturing Practice regulations in the U.S.
Segmentation Analysis:
The global topical drug delivery market has been segmented based on product, route of administration, facility of use, and regions.
By Product
The product segment includes semi-solid, liquid, solid, and transdermal products. The semi-solid formulations segment led the Topical drug delivery market with a market share of around 48.22% in 2021. Semi-solid formulations include all ointments, gels or jellies, creams, rigid foams, pastes, and emulsions. The growth of this segment is mainly driven by the fact that semi-solid products have been mainly manufactured in the past several years to distribute cosmetics, pharmaceutical drug products, and health supplements. In addition, the factors such as the increased prevalence of skin diseases and rising consumer demand for self-administration have boosted the growth of this segment.
By Route of Administration
The route of administration segment includes dermal drug delivery, ophthalmic drug delivery, rectal drug delivery, vaginal drug delivery, and nasal drug delivery. The dermal drug delivery segment led the topical drug delivery market with a market share of around 56.8% in 2021. This is attributed to the fact that dermal drug delivery has comparatively more benefits and convenience than the oral route of administration, and improves the efficacy and safety of the drug. In addition, such type of drug delivery ensures pain-free self-administration for the patients. The features mentioned above associated with dermal drug delivery fuel the growth of this segment.
By Facility of Use
The facility of use segment includes home care settings, hospitals & clinics, burn centers, and other facilities. The home care settings segment led the topical drug delivery market with a market share of around 48.98% in 2021. The rise in the need for self-administration of drugs and the growing geriatric population has mainly driven the growth of this segment. In addition, the cost-effective benefits of home health care services have boosted demand for topical drug delivery in home care settings. Moreover, several such settings have boosted dramatically due to the emergence of the COVID-19 pandemic. This factor has further created lucrative growth opportunities for the segment.
By Regional Analysis:
The regions analyzed for the Topical drug delivery market include North America, Europe, South America, Asia Pacific, and the Middle East, and Africa. North America region dominated the Topical drug delivery market and held a 36.22% share of the market revenue in 2021.
Global Topical Drug Delivery Market- Country Analysis:
Germany's Topical drug delivery market size was valued at USD 22.15 billion in 2021 and is expected to reach USD 43.66 billion by 2029, at a CAGR of 9.1% from 2022 to 2029.
In Europe, Germany is one of the leading shareholders in the topical drug delivery market. In addition, the huge healthcare spending by the government in this country has been a major contributor to the market growth. Furthermore, the increased prevalence of skin diseases such as acne vulgaris has driven the demand for topical drug delivery. In addition, the emergence of innovative topical drugs in the country creates lucrative growth opportunities for the market. For instance, in October 2021, Almirall, the Spanish dermatology company, launched its Klisyri (tirbanibulin) ointment in both the UK and Germany.
China's topical drug delivery market size was valued at USD 40.28 billion in 2021 and is expected to reach USD 78.80 billion by 2029, at a CAGR of 9.0% from 2022 to 2029. The factors such as the aging population, increasing consumer income, and government initiatives have driven the growth of the China topical drug delivery market. In addition, China accounts for about 40% of all active pharmaceutical ingredients (APIs) used globally in the global pharmaceutical manufacturing supply chain. In addition, the number of Chinese facilities that produce APIs for the U.S. have increased significantly over the past decade. This factor has been a primary contributor to this country's topical drug delivery industry revenue.
Moreover, in June 2020, The National Medical Products Administration (NMPA) in China approved Dupixent, a topical prescription medicine for treating moderate-to-severe atopic dermatitis in adults. Rising approval for topical drugs in the country for the treatment of skin disorders has further boosted the growth of the market.
India's topical drug delivery market size was valued at USD 13.49 billion in 2021 and is expected to reach USD 27.47 billion by 2029, at a CAGR of 9.5% from 2022 to 2029. India is one of the highest growing economies in Asia. The increasing population with skin disorders, rising incidences of burn injuries, and ongoing demand for at-home healthcare and self-administration of drugs have driven India's topical drug delivery market.
Furthermore, in July 2022, Glenmark Pharmaceuticals, an Indian multinational pharmaceutical company under the brand name “MINYM,” launched India’s first topical Minocycline 4% Gel, which is focused on the treatment of moderate to severe acne. The emergence of such topical drug products in the country further boosts the market growth.
Key Industry Players Analysis:
To increase their market position in the global topical drug delivery business, top companies are focusing on tactics such as adopting new technology, mergers & acquisitions, product developments, collaborations, and partnerships, joint ventures, etc.
Latest Development:
Report Metrics
Report Attribute |
Details |
Study Period |
2021-2029 |
Base year |
2021 |
CAGR (%) |
9.3% |
Market Size |
201.40 billion in 2021 |
Forecast period |
2022-2029 |
Forecast unit |
Value (USD) |
Segments covered |
Product, route of administration, facility of use, and Regions |
Report Scope |
Revenue forecast, competitive landscape, company ranking, growth factors, and trends |
Companies covered |
Glenmark Pharmaceuticals Ltd., Galderma, Johnson & Johnson Private Limited, GlaxoSmithKline Plc., Bausch Health Companies Inc., Hisamitsu Pharmaceuticals Inc., Cipla, Bayer AG, and Viatris Inc. (Mylan N.V.), 3M. among others |
By Product |
|
By Route of Administration |
|
By Facility of Use |
|
Regional scope |
|
Scope of the Report
Global Topical Drug Delivery Market by Product:
Global Topical Drug Delivery Market by Route of Administration:
Global Topical Drug Delivery Market by Facility of Use:
Global Topical Drug Delivery Market by Region:
Global Topical drug delivery market size was USD 201.40 billion in 2021
Global topical drug delivery market is expected to reach USD 403.08 billion by 2029, at a CAGR of 9.3% from 2022 to 2029
The home care settings segment led the Topical drug delivery market with a market share of around 48.98% in 2021
Increasing prevalence of diabetes, rising occurrence of burn injuries, and an upsurge in the prevalence of dermal diseases are primarily driving the growth of the Topical drug delivery market.
Leading market players active in the global Topical drug delivery market are Glenmark Pharmaceuticals Ltd., Galderma, Johnson & Johnson Private Limited, GlaxoSmithKline Plc., Bausch Health Companies Inc., Hisamitsu Pharmaceuticals Inc., Cipla, Bayer AG, Viatris Inc. (Mylan N.V.), 3M among others.
The global topical drug delivery market has been segmented based on product, route of administration, facility of use, and regions
Political Factors- The factors such as the aging population, increasing consumer income, and government initiatives have driven the growth of the China topical drug delivery market. In addition, China accounts for about 40% of all active pharmaceutical ingredients (APIs) used globally in the global pharmaceutical manufacturing supply chain. In addition, the number of Chinese facilities that produce APIs for the U.S. have increased significantly over the past decade. This factor has been a primary contributor to this country's topical drug delivery industry revenue.
Economical Factors- The world has been observing an upsurge population of common skin conditions such as acne, benign tumors, contact dermatitis, psoriasis, cancers, and atopic dermatitis (also called eczema). For instance, according to the American Academy of Dermatology, 84.5 million (one in four) people in the U.S. were impacted by skin diseases that accounted for about $75 billion in costs to the U.S. health care system in the form of preventative, medical, and prescription & non-prescription drug costs.
Social Factor- This is mainly attributed to increased preference for pain-free drug delivery, prevalence of skin diseases, and an upsurge in demand for self-administered drugs. The prevalence of skin diseases has been one of the prominent factors contributing to the demand for topical drug delivery in the region. For instance, Acne is a significantly common skin condition across the U.S. which and affects more than 50 million people annually. In addition, the factors such as favorable regulations and technically innovative healthcare facilities across the U.S. and Canada boost the market growth.
Technological Factors- Some of the other factors that drive the market include the ease of drug delivery and technological advancements and innovations. In March 2019, Amneal Pharmaceuticals introduced the generic version of Exelon Patch (Rivastigmine Transdermal System), 4.6 mg/24 hours, 9.5 mg/24 hours, and 13.3 mg/24 hours. It is used for the treatment of dementia caused due to Alzheimer's and Parkinson's disease. Such innovations are expected to flourish the market growth over the projection period.
Environmental Factors- There is a significant prevalence of skin diseases due to increasing pollution and rising global warming in the general population across different regions of the globe. The world has been observing an upsurge population of common skin conditions such as acne, benign tumors, contact dermatitis, psoriasis, cancers, and atopic dermatitis (also called eczema). For instance, according to the American Academy of Dermatology, 84.5 million (one in four) people in the U.S. were impacted by skin diseases that accounted for about $75 billion in costs to the U.S. health care system in the form of preventative, medical, and prescription & non-prescription drug costs.
Legal Factors- Galderma S.A., a Swiss pharmaceutical company, announced the introduction of EPSOLAY Cream, 5% in the U.S. after the approval by the U.S. FDA on April 22, 2022. According to the company, this cream is a proven topical treatment for relieving the bumps and blemishes of rosacea. Johnson & Johnson, an American multinational corporation, introduced the J&J Centers for Global Health Discovery. This is a research partnerships network to address worldwide health challenges. Glenmark Pharmaceuticals, an Indian multinational pharmaceutical company under the brand name “MINYM,” launched India’s first topical Minocycline 4% Gel, which is focused on the treatment of moderate to severe acne.
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